Buy Desmethylprodine (MPPP)

What is Desmethylprodine (MPPP)

Desmethylprodine or 1-methyl-4-phenyl-4-propionoxypiperidine (MPPP, Ro 2-0718) is an opioid analgesic drug developed in the 1940s by researchers at Hoffmann-La Roche. It is an analog of pethidine (meperidine). Chemically, it is a reversed ester of pethidine which has about 70% of the potency of morphine. Unlike its derivative prodine, it was not reported to exhibit optical isomerism. It was reported to have 30 times the activity of pethidine and a greater analgesic effect than morphine in rats, and it was demonstrated to cause central nervous system stimulation in mice.

History of Desmethylprodine (MPPP)

Desmethylprodine was first synthesized in 1947 at Hoffman-LaRoche Laboratories by Albert Ziering and John Lee. They found that it produced effects similar to morphine when administered to rats. Ziering had been searching for synthetic painkillers that were less addictive than morphine. The new drug was a slight variant of pethidine. This research produced the analgesic alphaprodine (Nisentil, Prisilidine), a very closely related compound.

How to Buy Desmethylprodine (MPPP)

You can buy Desmethylprodine (MPPP) and other research chemicals here at RAREmolecules. All of our chemicals are third party lab tested. If you wish to see HNMR results for Desmethylprodine (MPPP) or any other chemical, just email us at

Responsible Research with Desmethylprodine (MPPP)

Always practice responsible research. You should read and educate yourself before undertaking research with any chemical. The Psychonaut Wiki has some very helpful resources and information about Desmethylprodine (MPPP). Never conduct research with a chemical without learning about it first.

Desmethylprodine (MPPP) and all other chemicals are strictly for research purposes only and not for human consumption.

Keep Desmethylprodine (MPPP) in a cool, dry place away from sunlight.

Desmethylprodine (MPPP) stock last updated at: November 2024

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