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4-Fluoroamphetamine is a substituted amphetamine that offers effects somewhere between those of amphetamine and MDMA. It’s been a member of the research chemical market since the late 2000s. It has at times been a more popular research chemical because it does have a unique and potentially desirable effect profile.
Oral
Light: 25 – 50 mg
Common: 50 – 100 mg or 100 – 150 mg
Strong: 150+ mg
The common dose range depends on what effects you're looking for. A lower amount (50 – 100 mg) is better for productivity, while a higher amount (100 – 150 mg) usually makes the drug more recreational.
Total: 4 – 7 hours (at least somewhat longer for the stimulation vs. entactogen activity)
Onset: 20 – 40 minutes
Euphoria, Mood improvement, Music enhancement, Increased talking, Physical euphoria, Disinhibition, Increased empathy, Increased sociability
It’s generally described as a cross between amphetamine and MDMA. The effects are cleaner and more entactogenic than amphetamine, but definitely not as entactogenic as MDMA.
The wakefulness is equivalent to or greater than MDMA, as is the case with some of the pro-social effects. Users don’t report the stimulation to be very forced or uncomfortable in most cases.
As was already mentioned, the effects are dose-dependent. It’ll be primarily like amphetamine under 100 mg and a bit more MDMA-like over 100 mg.
Users tend to report a calm mindset with the drug and the chance of anxiety or agitation appears lower than with amphetamine. It’s often very pro-social with common or strong doses. An MDMA-like floatiness may be present.
The effects often have a wave-like nature, meaning there can be short periods where it feels like you’re much closer to sober. 4-FA has a smooth onset period and typically doesn’t produce a negative comedown or strong negative day-after effects.
If you’re taking a more recreational amount, the main effects will last 4-5 hours and be followed by more amphetamine-like stimulation for a few more hours.
It’s not going to be particularly useful as a productive stimulant when over 100 mg is used. Around 50 to 75 mg is reportedly useful as a productivity aid, similarly to common amounts of amphetamine. Also, it may be productive once the core entactogenic-like effects have worn off with higher doses.
A 2015 survey of 249 people in the Netherlands gives some idea of the typical effects and how 4-FA is used. Most people reported taking it in festivals, dance parties, and clubs. They primarily obtained it through friends or online shops.
77.1% used the drug because of its specific effects, not because of its legal status. Most participants first reported taking it around 2013.
Oral was the most common route of administration (92.8%). 100 – 150 mg was the most common dose range, though close to 20% used over 150 mg.
Participants said it lasted either 4 to 6 hours or 6 to 8 hours.
The actual effect scores were between those for MDMA and amphetamine.
Compared to amphetamine
- Less irritability
- Greater talkative and pro-social effects
- Lower “craving” score
- Similar for alertness and stimulation
- Greater euphoria and “connectedness to others”
- Greater “changes in sensory perception.”
Compared to MDMA
- Lower intensity, confusion, and dizziness
- Lower “craving”
- Lower euphoria and “connectedness to others”
- Lower “changes in sensory perception.”
4-Fluoroamphetamine = 4-FA; 4-FMP; PFA; Para-Fluoroamphetamine; Molly’s Mosquito
PubChem: 9986
Molecular formula: C9H12FN
Molecular weight: 153.2 g/mol
IUPAC: 1-(4-fluorophenyl)propan-2-amine
You can buy 4-FA and other research chemicals here at RAREmolecules. All of our chemicals are third party lab tested. If you wish to see HNMR results for 4-FA or any other chemical, just email us at
Always practice responsible research. You should read and educate yourself before undertaking research with any chemical. The Psychonaut Wiki has some very helpful resources and information about 4-FA. Never conduct research with a chemical without learning about it first.
4-FA and all other chemicals are strictly for research purposes only and not for human consumption.
Keep 4-FA in a cool, dry place away from sunlight.
4-FA stock last updated at: November 2024
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